Senior Dir, In-Vivo & Non-Clinical Pharmacology

Working with UsChallenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Role OverviewBristol Myers Squibb is seeking a strategic and scientifically grounded leader to serve as the Senior Director for In-Vivo & Non-Clinical Pharmacology. This leader will partner deeply with Research leadership and the Pharmacology, DMPK, Toxicology, and Translational Science units to deliver the applications, workflow capabilities, AI, and supporting data flows that enable non-clinical decisions across in-vivo biology, DMPK, ADME, non-clinical safety, toxicology, and bioanalytical science.The role is focused on the digital and analytical capability layer that helps Research generate, interpret, and act on non-clinical evidence, rather than owning the underlying scientific operations themselves. In close partnership with BMS’s R&D Data organization and peer BI&T leaders, this role will help build an integrated, multi-year environment in which non-clinical evidence flows cleanly into translational, clinical pharmacology, regulatory, and Development decision-making.Reporting to the Vice President, Research Business Insights & Technology, this leader will operate as part of a unified BI&T leadership team and act as a trusted partner to Research leadership, translating scientific needs into scalable, integrated technology solutions.Mission & ImpactEnable higher-confidence candidate progression decisions through integrated non-clinical applications, AI, and workflow supportModernize PK/PD, DMPK/ADME, toxicology, and bioanalytical decision environments with predictive and AI-enabled capabilitiesImprove how non-clinical evidence is captured, connected, and reused to support downstream translational, clinical pharmacology, regulatory, and Development decisionsAdvance predictive safety, translational modeling support, histopathology image AI, and agent-enabled study workflows where they create clear scientific valueReduce fragmentation across non-clinical workflows and improve decision speed, traceability, and reuse of evidenceKey ResponsibilitiesPartner with Pharmacology, DMPK, Toxicology, and Translational Science leaders to shape and deliver the technology roadmap supporting non-clinical decisionsLead deployment of GenAI, agentic, and predictive AI/ML capabilities for non-clinical workflows, including predictive safety, in silico DMPK, histopathology image AI, and study design supportEnsure non-clinical data is captured with high fidelity in source systems and flows cleanly to downstream curation by the R&D Data organizationPartner with scientific, quality, and operational stakeholders to ensure applications appropriately support animal welfare data, IACUC-related processes, and study-governance workflowsEnable non-clinical safety signal detection and risk characterization through modern analytics, integrated data flows, and decision-support toolsPartner with Development teams so that clinical findings flow back into non-clinical model validation and refinementEnsure operational excellence and reliability of non-clinical applications, modeling environments, and analyticsLead and develop a team of scientific technologists, AI/ML engineers, product leaders, and application specialistsRequired Experience & QualificationsBachelor’s, Master’s, or Ph.D. in Pharmacology, Pharmaceutical Sciences, Biology, Bioinformatics, or related field (Ph.D. preferred)12–15+ years in pharmaceutical R&D with strong exposure to preclinical and translational scienceDeep understanding of in-vivo pharmacology, DMPK/ADME, safety/toxicology, and bioanalytical workflowsProven experience leading applications, digital products, or AI-enabled capabilities in non-clinical R&D, including predictive safety, in silico DMPK, or histopathology image AIExperience working in GLP-adjacent regulated environments and with IACUC-related processesProven leadership at Director or Senior Director levelCritical CapabilitiesScientific Depth in Non-Clinical Pharmacology — Engages deeply with non-clinical scientific leaders and understands experimental design, data, and interpretationStrategic Partnership — Acts as a trusted partner to Research leadership, translating scientific needs into integrated technology solutionsAI / Predictive Modeling Strategy — Fluent in predictive safety, in silico DMPK, image AI, and agentic capabilities for non-clinical workflowsRegulated Workflow Fluency — Fluent with GLP, IACUC, and non-clinical safety governanceEnd-to-End Pipeline Thinking — Understands how non-clinical data impacts downstream Development and decision-makingLeadership & Change AttributesStrong ability to partner with senior scientific leaders and act as a trusted advisorProven experience driving organizational and technology transformation in scientific environmentsAbility to translate complex scientific and technical concepts into actionable strategiesExperience navigating matrixed, global organizationsCommitment to building a high-performing, collaborative team cultureWhat Differentiates Top CandidatesExperience leading non-clinical pharmaceutical sciences digital, AI, or application transformation initiativesDemonstrated success building