Senior Director, U.S. Obesity, Portfolio & GTM Strategy

THE OPPORTUNITYObesity is one of the most consequential and rapidly evolving therapeutic areas in medicine — and Pfizer is building a differentiated portfolio to meet this moment.The Senior Director, U.S. Obesity, Portfolio & GTM Strategy is a senior upstream product marketing role responsible for building the commercial foundation for Pfizer's emerging obesity franchise. This leader will define how Pfizer's assets are positioned, how customers are segmented and targeted, and how clinical evidence is translated into compelling brand strategy — all ahead of a landmark US launch.The role sits at the intersection of science, strategy, and marketing craft. It requires the ability to turn ambiguous data into clear positioning, build cross-functional alignment around a brand vision, and create go-to-market frameworks that are both strategically sound and ready to execute. This is a franchise-defining role for a product marketer who thrives in white space.KEY RESPONSIBILITIESBrand Strategy & PositioningLead development of US portfolio brand strategy for the obesity franchise — including positioning architecture, value proposition frameworks, and message platform development across consumer and HCP audiences.Translate clinical data, patient insights, and competitive dynamics into differentiated, evidence-grounded positioning that resonates with key customer segments.Lead early-stage brand planning activities, including customer journey mapping, insight generation, and narrative development in partnership with downstream marketing leads.Build and evolve portfolio scenario plans that anticipate pipeline evolution, competitive launches, and market disruption.Go-to-Market DevelopmentArchitect the foundational GTM strategy for Pfizer's US obesity portfolio, defining channel and customer engagement models across HCP, consumer, and payer audiences.Partner with Medical Affairs, Market Access, and HEOR to ensure brand strategy is grounded in clinical evidence and aligned to the evolving payer and policy landscape.Drive rigorous assessment of emerging business models — including payer dynamics, IDN models, and digital health integration — to inform a durable and differentiated market approach.Lead go-to-market development in close partnership with Sales, Medical, and Commercial Operations.Market Intelligence & Insight ActivationCommission, synthesize, and activate primary and secondary research programs to generate actionable insights across the patient journey, competitive environment, and customer needs — and translate those insights directly into brand and marketing decisions.Define and operationalize segmentation frameworks that identify and size the highest-value patient populations and customer targets, in partnership with Global Commercial Analytics.Establish ongoing market monitoring capabilities that keep strategic plans continuously calibrated to real-world signal.Global Partnership & Cross-Functional LeadershipServe as a key US commercial voice in partnership with global portfolio and strategy leads, ensuring US market priorities shape cross-market planning and portfolio decisions.Contribute to globally consistent frameworks — including positioning architecture and competitive response playbooks — while adapting for US market nuance.Represent the obesity portfolio strategy function in senior commercial leadership forums and cross-functional governance bodies.Oversee multiple agencies and partners to execute against high visibility deliverables and deliver more efficient and effective workQUALIFICATIONSRequired:12+ years of progressive experience in pharmaceutical, biotech, health tec or consumer commercial organizations with demonstrated expertise in upstream product marketing or brand strategy.Proven track record translating clinical data and customer insights into compelling positioning and go-to-market strategy in a complex, pre-launch or high-growth environment.Deep experience leading segmentation, message platform development, and brand planning — not just informing them.Strong market research and competitive intelligence fluency, with the ability to turn ambiguous data into clear strategic and creative direction.Demonstrated ability to operate and influence effectively in highly matrixed organizations, including senior executive engagement.Strong executive presence and communication skills; adept at presenting complex brand strategy to C-suite audiences.Bachelor's degree required.Preferred:Experience in metabolic, cardiovascular, or endocrine therapeutic areas; prior obesity franchise experience is a meaningful differentiator.Familiarity with GLP-1 landscape dynamics, digital therapeutics integration, and emerging payer and DTP models.MBA or advanced degree.Prior experience in brand management, management consulting, or agency strategy with a healthcare focus.LEADERSHIP ATTRIBUTESThe ideal candidate brings a rare combination of marketing craft and strategic depth — someone who can see around corners, build a brand vision from the ground up, and drive alignment across a diverse set of stakeholders. We are looking for a leader who:Builds brands with rigor — grounding positioning in evidence, insight, and competitive reality.Thinks creatively and commercially — bringing both analytical precision and genuine marketing instinct to every decision.Thrives in ambiguity and treats white space as an opportunity, not an obstacle.Leads with influence — earning trust and alignment without relying on authority.Communicates with conviction — distilling complex ideas into narratives that move people and drive decisions.Invests in people — developing talent, fostering psychological safety, and creating conditions for the team to do their best work.WHY THIS ROLEThis is not a role for someone who wants to optimize an existing launch. It's for someone who wants to build one — in one of the most dynamic and competitive therapeutic areas in the industry, at a company with the scale and ambition to lead it.If t