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Principal Engineer - Global Reliability Network Lead (Remote)

at Amgen

Amgen2 LocationsPosted 2026-06-01
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Job description

Career CategoryEngineeringJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Principal Engineer - Global Reliability Network LeadWhat you will doLet’s do this. Let’s change the world! In this vital role, you will lead Amgen’s Global Reliability Network as part of Engineering Operations Services (EOS) department, helping sites turn reliability data, maintenance history, failure trends, and equipment performance insights into actions that improve asset reliability, equipment availability, maintenance effectiveness, and operational capacity. You will also serve as the business lead for the CMMS Asset Performance Monitoring module and reliability-focused equipment insight tools across Amgen’s manufacturing network. Occasional on-site presence at the nearest Amgen operation site may be requested based on business needs.Specific responsibilities include but are not limited to:Lead the Global Reliability NetworkLead a network of site reliability engineers, maintenance leaders, system owners, and technical SMEs.Develop and execute the Reliability Network strategy, goals, milestones, and maturity plans.Share reliability KPIs, bad actor trends, equipment improvements, lessons learned, and reusable solutions.Represent reliability priorities and recommendations in senior engineering governance forums.Turn data insights into equipment improvementsUse CMMS data, Asset Performance Monitoring, Plant Pulse, PdM findings, and site input to identify recurring failures, high-risk assets, downtime drivers, and bad actors.Convert reliability insights into corrective actions, equipment improvements, PM/PdM optimization, spare parts strategies, and capital recommendations.Track improvement actions, verify benefits, and scale successful practices across sites.Advance asset criticality and maintenance strategyDefine and maintain a standard risk-based asset criticality approach across sites.Use criticality to prioritize maintenance strategies, work execution, spare parts, lifecycle planning, and performance monitoring.Standardize maintenance strategies based on criticality, failure modes, operating context, and performance history.Support RCM, FMEA/FMECA, PM optimization, predictive maintenance, and condition-based maintenance approaches.Lead Asset Performance Monitoring and PlantPulse adoptionDefine business requirements for asset health, criticality, failure modes, risk ranking, performance monitoring, and continuous improvement.Partner with SAP EAM, Technology/IS, site engineering teams, the Reliability Network, and SMEs to support deployment, training, adoption, and data quality.Serve as PlantPulse business owner to ensure tools address reliability pain points, support troubleshooting, and generate actionable equipment insights.Connect reliability to business valuePartner with OPEX teams to identify reliability improvements that unlock capacity and reduce downtime.Translate recurring failures and reliability constraints into business impact.Support lifecycle risk visibility for critical assets, including deterioration, obsolescence, maintenance cost, reliability concerns, and end-of-life planning.Integrate reliability principles into capital projects from conceptual design through turnover.What we expect of youWe are all different, yet we all use our unique contributions to serve patients. The Principal Engineer professional we seek is a collaborative individual contributor leader with these qualifications.Basic Qualifications:Doctorate degree & 2 years of engineering industry experienceORMaster’s degree & 4 years of engineering industry experienceORBachelor’s degree & 6 years of engineering industry experienceORAssociate’s degree & 10 years of engineering industry experienceORHigh school diploma/GED & 12 years of engineering industry experienceBeyond that, additional preferred qualifications are: Bachelor’s degree in Engineering.Experience in maintenance, reliability, engineering, asset management, manufacturing operations, and/or engineering digital transformation.Experience leading cross-functional initiatives in site, multi-site, or global environments.Strong knowledge of CMMS/EAM and asset performance monitoring systems, such as SAP, Maximo, or equivalent.Working knowledge of asset criticality, RCM, FMEA/FMECA, RCA, PM optimization, PdM, condition-based maintenance, and reliability KPIs.Ability to translate site needs into scalable business processes, digital product requirements, and improvement actions.Strong stakeholder management, communication, network leadership, and change leadership skills.Experience with analytics or dashboarding tools such as Power BI, Spotfire, SAP Analytics Cloud, or equivalent.Experience in GMP, biopharmaceutical manufacturing, GxP research, laboratory, or other regulated operations.Familiarity with ISO 55000, ISO 14224, SMRP, Uptime Elements, or similar reliability and asset management frameworks.Certification such as CMRP
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