Senior Principal Scientist, Cardiovascular, Translational Development

Working with UsChallenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.Position SummaryTranslational Development is part of the Global Research organization in BMS and leads late-stage clinical, pharmacological and translational research and development activities for the pipeline and supports late-stage portfolio for regulatory, translational development and life cycle management. Translational Development drives strategy across core therapeutic areas at BMS including hematology, oncology, immunology, cardiovascular and neuroscience. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics. Incumbents with deep training and education in cardiovascular, or related disease areas, including but not limited to neurocardiac research.Key Responsibilities:Designs and implements program-specific development biomarker/translational plansResponsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicableManages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROsPrepares and delivers internal and external translational/biomarker presentationsMaintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as neededKeeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biologyWorks with TM laboratory scientists and academic TLs to address nonclinical translational questions as neededParticipates/leads post-hoc biomarker analysis and publication effortsSupports regulatory submissions and regulatory interactions as neededParticipate in Diagnosis (PDx) biomarker assay development through collaboration with precision medicine groupQualifications & Experience:PhD with 5–8+ years of translational medicine and clinical biomarker experience, including 5+ years supporting early‑ and/or late‑stage clinical programs in biotech or pharma.Recognized expertise in translational biomarkers in cardiovascular or related disease areas, with experience in drug development and clinical trial initiation, conduct, and completion.Experience interacting with CROs and thought leaders to manage projects, timelines, and deliverables.Demonstrated scientific and project leadership experience, including working in cross‑functional teams, mentoring, and managing projects, with the ability to identify risks and implement contingency plans.Experience mining and interpreting datasets in collaboration with bioinformaticians to understand mechanism of action, disease pathophysiology, or patient segmentation hypotheses.Strong communication skills, including preparing and delivering presentations within the department, to governance and senior leadership, and externally as needed; recognizes and communicates cross‑functional issues across the organization.Ability to support multiple projects in a fast‑paced, collaborative environment, with strong organizational skills, attention to detail, and accurate record keeping.#LI-HybridIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:Brisbane - CA - US: $184,060 - $223,036 Cambridge Crossing: $184,060 - $223,036 Princeton - NJ - US: $160,060 - $193,949 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/. Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:Health Coverage: Medical, pharmacy, dental, and vision care.Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability prot