Senior Associate Scientist

Working with UsChallenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.The Protein Homeostasis Thematic Research Center at BMS is a fundamental Oncology research engine delivering oncology and hematology therapeutics to patients. The TRC has a major focus on exploiting BMS’ expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics. This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable.Position Responsibilities In the role as a Sr Associate Scientist within Molecular Pharmacology group, the ideal candidate:Develop and execute a range of assays to support structure–activity relationship (SAR) studiesDesign and implement biochemical and cell-based assays to enable target validation and mechanism-of-action (MOA) investigationsAnalyze, interpret, and present data in team meetings and potentially cross-functional forumsCollaborate effectively with cross-functional teams to drive project progress and achieve program objectivesExperience = Basic Qualifications: Bachelor’s Degree4+ years of academic and / or industry experienceOrMaster’s Degree2+ years of academic and / or industry experiencePreferred Qualifications: Technical and Scientific ExperienceAdvanced cell culture skills with hands-on experience in cell engineering and gene editing, including CRISPR, RNAi, gene overexpression, and lentiviral transductionExpertise in cell-based assays and high-throughput screening (HTS), including cell proliferation, cell cycle, apoptosis, 3D sphere formation, and senescenceExperience with molecular and cellular biology and biochemistry techniques, such as qPCR, immunofluorescence, Western blot, ELISA, MSD, and FACSExperience in MOA studies using integrative multi-omic approaches, including preparation of samples for proteomic, transcriptomic, and chromatin-binding studiesFamiliarity with key aspects of SAR support using a variety of biological assaysProven publication record as a major contributor or author is a plusAbility to design, plan, and execute scientific experiments with moderate supervisionStrong attention to detail and ability to follow laboratory procedures and execute bench experimentsProficiency in data analysis and visualization tools, including MS Office and GraphPad PrismProfessional Skills and Work RequirementsHighly motivated, innovative, and able to multitask effectively in a fast-paced, dynamic team environmentStrong communication, collaboration, and organizational skillsAbility to deliver high-quality data in a timely and well-organized mannerFlexibility to support business needs, including occasional weekend work, early starts, late end times, and learning new skill sets and techniquesThis position requires primarily on-site presence#LI-OnsiteIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:San Diego - CA - US: $100,480 - $121,756 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/. Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:Health Coverage: Medical, pharmacy, dental, and vision care.Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.​Work-life benefits include:Paid Time OffUS Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidaysBased on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.All global employees full and part-time who are activ