Senior Associate Scientist

Working with UsChallenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.The Protein Homeostasis Thematic Research Center at BMS is a fundamental Oncology research engine delivering oncology and hematology therapeutics to patients. The TRC has a major focus on exploiting BMS’ expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics. This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable.Position ResponsibilitiesIn the role as a Senior Associate Scientist within the Integrative Systems Pharmacology team, the ideal candidate will be responsible for but, not limited to:Develop, maintain, and passage mammalian cell lines and patient derived organoids, including the generation of overexpressing and knockout lines, for use in screening and functional assaysDesign and execute assays to assess cell growth, apoptosis, cell cycle progression, and protein expressionManage cryopreservation of tissues and cell linesIndependently analyze and interpret data and present results at project team meetings, group meetings, etc.Collaborate with colleagues in other functional areas including translational research, informatics and chemistry to pursue target validation experiments and support drug discovery effortsMaintain accurate electronic laboratory notebooks in a timely fashion and prepare technical reports, summaries, protocols, etc.Stay current with emerging AI tools and best practices relevant to drug discovery and contribute to the adoption of innovative computational approaches within the teamAssist in laboratory operation management dutiesExperience = Basic Qualifications: Bachelor’s Degree4+ years of academic and / or industry experienceOrMaster’s Degree2+ years of academic and / or industry experiencePreferred Qualifications:  Hands-on experience with mammalian cell culture, including standard 2D and preferably 3D culture systemsProficiency in plate-based cell assays, including CTG, apoptosis, and Incucyte imaging platformsExperience with transfection and viral transduction techniques, including overexpression and CRISPR-based knockout approachesFamiliarity with protein detection methods, including Western blotting; experience with WES/JESS ProteinSimple is a plusExcellent organizational skills and attention to detail, with a demonstrated ability to maintain accurate and thorough laboratory recordsEagerness to learn and apply new techniques, instrumentation, and methodologiesAbility to work both independently and collaboratively as part of a multidisciplinary teamProficiency in Microsoft Office Suite (Word, Excel, PowerPoint); experience with GraphPad Prism and FlowJo is a plus#LI-OnsiteIf you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Compensation Overview:San Diego - CA - US: $100,480 - $121,756 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/. Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:Health Coverage: Medical, pharmacy, dental, and vision care.Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.​Work-life benefits include:Paid Time OffUS Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidaysBased on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year ar